Anti-Cancer Nutrients & Supplements » Integrative Oncology Essentials

CoQ 10 may reduce the risk of developing melanoma and reduce recurrence

Posted by Brian Lawenda M.D. at 10:36 am

Apr 232012

Reports indicate anticancer activity with higher blood levels of CoQ 10 (reduced risk of melanoma development, recurrence and progression.) Why do we rarely hear about this? Very few human studies have been conducted to confirm these findings. (imagine that…no profit potential…no money to conduct this study)

What is CoQ 10?

CoQ 10 (also known as: coenzyme Q10, Q10, Vitamin Q10, Ubiquinone, Ubiquinol, Ubidecarenone) is an important protein made by the body, that is involved in cellular metabolism (converting the energy from fats and sugars into usable cellular energy) and as a protective antioxidant.

CoQ 10 stimulates the immune system

Numerous studies have reported on the immune stimulating effects of CoQ 10, although the mechanisms involved in this physiologic activity are not known.

http://www.ncbi.nlm.nih.gov/pubmed/1673841?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/10416052?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/101414?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/5478631?dopt=Abstract

CoQ 10 can suppress cancer cell growth

The mechanisms involved in this anticancer activity are not known.

http://www.ncbi.nlm.nih.gov/pubmed/4218125?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/653103?dopt=Abstract

CoQ 10 protects the heart from chemotherapy injury

Studies have demonstrated that CoQ 10 can protect heart tissue from the potentially damaging effects of a commonly used class of chemotherapy drugs, called anthracyclines (i.e. doxorubicin).

CoQ 10 blood levels correlate with the risk of developing melanoma

Researchers prospectively followed 117 early stage (none with metastatic disease) melanoma patients and 125 healthy volunteers (control group), and they discovered some remarkable differences. First, the CoQ 10 levels were significantly lower in patients than in control group. Second, those with CoQ 10 levels less than 0.6 mg/L (low) had a 790% increased risk of developing metastatic disease compared with those patients who had higher levels of CoQ 10; the time to develop metastases was also almost double in patients with CoQ 10 levels 0.6 mg/L or higher! Among the 82 melanoma patients with a low CoQ 10 level (less than 0.6 mg/L), 17 of them died during the study period…whereas, none of the patients with higher CoQ 10 levels died.

http://www.ncbi.nlm.nih.gov/pubmed/16443053

CoQ 10 has been reported to enhance the efficacy of interferon therapy for melanoma

One of the standard therapies for use in patients with advanced stages of melanoma (stages 3-4) is an immune stimulating agent, interferon (IFN). IFN stimulates the immune system to recognize and attack melanoma cells. Patients with early stage disease (stages 1-2) are not typically recommended to receive IFN after surgery, as this drug is difficult for many patients to tolerate due to various side effects and the potential benefit in reducing the risk of recurrence has not well-established in these early stages.

One enterprising group of oncologists postulated that by giving CoQ 10 to those with early stage melanoma, they might be able to further stimulate the immune system. What they found was incredible:

In their study, they gave 32 patients with early stage (stage 1-2) melanoma IFN (2 injections per day of 600,000 IU) plus 400mg per day of CoQ10 for 3 years after surgery, while 49 received only interferon. The patients were monitored for five years after their treatment ended. They reported that the patients who received the IFN + CoQ10 had a reduction in their risk of developing metastases by 10-times compared with those who received only IFN. Furthermore, the IFN + CoQ 10 patients had far fewer IFN-related side effects compared with the IFN only patients; 22% versus 82%, respectively.

Other cancers that might benefit from CoQ 10 supplementation:

Very small studies and case reports have suggested that CoQ 10 may help some cancer patients live longer, including patients with cancers of the breast, pancreas, lung, colon, rectum, and prostate. Although these reports are promising, they are unfortunately not high-quality studies, therefore not much weight can be placed on these results.

Note of caution…don’t take CoQ 10 during radiation therapy:

A mouse study demonstrated reduced anticancer activity of radiation therapy when supplemented with CoQ 10. Radiation therapy works by creating free radicals in cancer cells, which then interact with the DNA and cause cell death. It is believed that by supplementing with a potent antioxidant, such as CoQ 10, the free radicals created by radiation therapy will be diminished along with its’ anticancer efficacy. Read my review article on this in the Journal of the National Cancer Institute.

CoQ 10 side effects:

None-to-mild side effects, including mild insomnia, elevated liver enzymes, rashes, nausea, upper abdominal pain/heartburn, dizziness, sensitivity to light, irritability, headache, and fatigue.

Commonly prescribed medications can lower CoQ 10 levels:

Lipid lowering medications (such as lovastatin, pravastatin, simvastatin, gemfibrozil) and the oral diabetes medications (such as glyburide and tolazamide) are well-known to reduce CoQ 10 levels. Patients taking these medications should discuss with their primary care physician supplementation with CoQ 10.

Cautionary effects of CoQ 10:

CoQ 10 may reduce the efficacy of warfarin.

CoQ 10 may reduce insulin requirements in diabetics.

As CoQ 10 has not been exhaustively researched with every chemotherapy agent or combination of agents (it’s never going to happen), recognize that there is a possibility of interactions that can either increase or decrease the anticancer effectiveness of the chemotherapy agent. Always discuss any use of supplements with your oncology team prior to using them.

Dosing:

There are no established dosing guidelines. In human studies, supplementation doses and administration schedules have varied, but usually have been in the range of 90 to 390 mg/day (most common recommendation: 100-200 mg/day)

Most absorbable form of CoQ 10:

Ubiquinol absorbs up to 8 times greater than ubiquinone, and higher levels of ubiquinol remain in the blood far longer than ubiquinone.

CoQ 10 is fat soluble. It is more effectively absorbed when taken with a meal (particularly with lipids).

Additional Resources:

National Cancer Institute PDQ: CoQ 10

About Herbs, Botanicals and Other Products (Memorial Sloan-Kettering Cancer Center): CoQ 10

Wikipedia; CoQ 10

Medline Plus (National Library of Medicine): CoQ 10

CoQ 10 and Cancer Treatment (Life Extension)**although I like many of their products, this is still a supplement company**

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Anticancer Nutrition: Protein 101

Posted by Brian Lawenda M.D. at 1:42 pm

Apr 162012

The main point on protein is that you want to consume as much of your daily protein requirements from a variety of low fat sources, such as legumes (beans, peas, lentils, soy, nuts and nut butters), deep, cold-water fish (salmon, sardines, mackerel, cod), poultry (skin removed) and whey (a milk protein.) You don’t have to completely eliminate dairy and meat (particularly, red meat: beef, pork, lamb) from your diet to live an anticancer lifestyle, but you will need to limit the quantity you consume. Increasingly, the results of numerous studies are consistently suggesting that the most healthful overall diet (anti-cancer, anti-diabetes, anti-cardiovascular disease, anti-inflammatory, [...read more...]

Anticancer Nutrition: Fats 101

Posted by Brian Lawenda M.D. at 4:27 pm

Apr 092012

Dietary fats are essential components of our daily nutritional intake, but the amount and type of fats have a large impact on the development of cancer, cardiovascular disease, systemic inflammation, oxidation, immunity and numerous other important aspects of health and disease. This article provides a basic understanding of the various dietary fats and their relevance in anticancer nutrition. General Recommendations: Limit total fat intake and avoid trans fats Increase your intake of foods high in omega-3s (i.e. cold-water, deep sea fish and nuts, flax seed) Limit foods that are higher in omega-6 fatty acids (grain-fed animal meat) Avoid foods that [...read more...]

Anticancer Nutrition: Sugar & Insulin 101

Posted by Brian Lawenda M.D. at 12:45 am

Apr 042012

Anticancer Nutrition: Sugar & Insulin 101

The Basics: How does insulin work? In a healthy person, insulin helps turn food into energy — in an efficient manner. The stomach breaks down carbohydrates from food into sugars, including glucose. Glucose then enters the bloodstream, which stimulates the pancreas to release insulin in just the right amount. Insulin, a hormone, allows glucose to enter cells throughout the body, where it is used as fuel. Excess glucose is stored in the liver. What is IGF-1 (Insulin-Like Growth Factor-1)? IGF-1 is an important protein (hormone) that stimulates cells (including many cancer cells) to grow and is involved in multiple aspects of [...read more...]

Anticancer Nutrition: 7 Important Anti-Cancer Diet Tips

Posted by Brian Lawenda M.D. at 5:28 pm

Apr 032012

Anticancer Nutrition: 7 Important Anti-Cancer Diet Tips

Point #1: Limit The Amount Of Fat In Your Diet Studies suggest that diets higher in the bad fats: Increase the risk of developing cancer (especially more aggressive cancers) and cancer progression. Suppress the immune system and increase inflammation in the body. Increase the risk of dying from numerous cancers (i.e. breast, prostate, colorectal, lung) Bad fats include the trans fats (partially and fully hydrogented fats) and saturated fats: Try to limit your intake of saturated fats to 5-10% of your total daily calories. Transfats are bad. There is no reason to ever consume them. The risk of breast cancer almost [...read more...]

What Is Integrative Oncology? (Free Patient Guide)

Posted by Brian Lawenda M.D. at 3:17 pm

Apr 032012

What Is Integrative Oncology? (**Free Patient Guide**)

Integrative Oncology uses the best evidence-based treatments (i.e. surgery, chemotherapy, radiation therapy, acupuncture, massage, stress reduction, herbal/botanicals, etc.) with the following goals: Treating the cancer Preventing recurrence Reducing side effects and symptoms Integrative Oncology encourages living a healthy lifestyle to help the body in its’ innate abilities to fight and prevent cancer. This can be accomplished by learning strategies to reduce stress, increasing physical activity and eating healthfully (“anti-cancer diet & nutrition.”) Practicing these lifestyle changes leads to beneficial “anti-cancer” effects: Strengthening the immune system Decreasing inflammation throughout the body Reducing (free radical) oxidative damage to cells Decreasing hormonal stimulation of cancer cells Treatments are selected using a customized approach for each person [...read more...]

One of the best videos you will see on integrative oncology & living an “anti-cancer” lifestyle

Posted by Brian Lawenda M.D. at 1:19 pm

Mar 142012

One of the best videos you will see on integrative oncology & living an "anti-cancer" lifestyle

Dr. David Servan-Schreiber was one of the most influential physicians in our field of integrative oncology, and in this wonderful lecture you will learn why. His book, Anti-Cancer: A New Way Of Life, remains an international best-seller and one that I recommend to most of my patients. If you are interested in learning about integrative oncology and how to reduce your risk of cancer development, recurrence and progression, I strongly recommend you watch this video. This lecture is worth your time, and it will blow your mind. You can find the latest edition (December 31, 2009) of his book [...read more...]

Consuming foods rich in omega-3 fatty acids reduces fatigue & inflammation in breast cancer survivors

Posted by Brian Lawenda M.D. at 6:58 pm

Mar 132012

Consuming foods rich in omega-3 fatty acids reduces fatigue & inflammation in breast cancer survivors

A new study, reported in the Journal of Clinical Oncology, found that breast cancer survivors have less fatigue if they consumed higher quantities of foods rich in omega-3 fatty acids (a major component of an “anti-inflammatory diet“). The researchers studied the potential effects of dietary omega-3 versus omega-6 in a population of 633 breast cancer survivors. Specifically, the authors wanted to know if a higher intake of omega-3 foods has a beneficial impact on fatigue, a common complaint of breast cancer survivors. Cancer related fatigue is thought to be due, in large part, to systemic inflammation that occurs as a [...read more...]

Cannabis and Cancer: 1 plant versus 5 common symptoms that affect cancer patients

Posted by Brian Lawenda M.D. at 7:32 pm

Jan 282012

Cannabis and Cancer: 1 plant versus 5 common symptoms that affect cancer patients

This is a completely apolitical blog entry on the science of the medical efficacy of Cannabis (marijuana) in oncology. Cannabis is plant that is classified in the U.S. as a controlled substance with an “increased potential for abuse and no known medical use” (Schedule 1). By federal law, possessing Cannabis, is illegal in the U.S. Although U.S. federal law prohibits the use of Cannabis, 16 states and the District of Columbia permit its use for certain medical conditions with a physicians’ prescription. That said, doctors in these states may not legally do so without violating federal law and can lose their federal license to [...read more...]

Employing a multi-pronged anticancer approach using natural supplements and whole foods

Posted by Brian Lawenda M.D. at 11:52 am

Dec 022011

Employing a multi-pronged anticancer approach using natural supplements and whole foods

The data supporting anticancer activity in natural supplements is extensive. Unfortunately, oncologists and patients are hampered by the paucity of high-quality clinical trials in deciding which supplements might improve clinical outcomes. Designing and conducting these studies is expensive and will take many years before we have answers (i.e. which supplements work for which cancers, what doses are effective, how do they interact with other therapies/compounds, etc.) These studies can be done and must be done, but what do we do in the meantime? Most oncologists suggest to their patients that they simply consume a diet containing a wide-variety of phytonutrient [...read more...]

Vitamin E: Is it safe for men anymore?

Posted by Brian Lawenda M.D. at 5:17 pm

Oct 142011

In light of the recently reported SELECT study, many patients are asking this question. Here is my short response: The data from the recently reported SELECT trial show a 17% increased risk of developing prostate cancer with 400 IU’s of vitamin E per day (but no difference in risk when men took both selenium and vitamin E vs. placebo). No data have yet been reported on the baseline serum levels of alpha-tocopherol among the men in this trial, which will be quite important. Researchers are scratching their heads trying to understand these counterintuitive data. Conflicting data: The data from [...read more...]

Amazing anti-cancer compound derived from the French Lilac: Galega officianalis (metformin)

Posted by Brian Lawenda M.D. at 12:39 pm

Aug 292011

Amazing anti-cancer compound derived from the French Lilac: Galega officianalis (metformin)

Metformin is a medication derived from the herb Galega officinalis (French lilac, also known as Goat’s Rue or Italian Fitch) and has been used as a traditional botanical (tea infusion) for over 3,000 years to relieve polyuria (frequent urination) and halitosis (sweet odor on the breath), both are now well known symptoms of diabetes. Approved for the treatment of hyperglycemia in Britain since the late 1950′s, Canada in the 1970′s and U.S. in 1995, metformin is the most widely prescribed diabetes drugs (over 120 million prescriptions filled yearly worldwide). Although the mechanism of action of metformin in diabetes is only partially understood, metformin treatment [...read more...]

Testosterone replacement therapy in men with prostate cancer: An oncologist’s perspective

Posted by Brian Lawenda M.D. at 5:41 pm

Jul 252011

Testosterone replacement therapy in men with prostate cancer: An oncologist's perspective

“Does testosterone replacement therapy (TRT) increase the risk of my prostate cancer coming back?” It seems that this question is coming up more often these days among patients who have completed treatment for prostate cancer. The Background: Very effective direct to consumer marketing campaigns touting the benefits of TRT and “bio-identical hormone therapy” (i.e. Dr Life’s Cenegenics, BodyLogicMD, etc.) have peeked the interest of many men who are starting to feel the mental and physical effects of ‘aging’. Popular TV news, talk shows and radio programs have spread the word about so the called “male menopause” or “andropause”. As part [...read more...]

Integrative Oncology: Given the choice, would you really want any other approach to the treatment of cancer?

Posted by Brian Lawenda M.D. at 10:51 pm

Jul 102011

Integrative Oncology: Given the choice, would you really want any other approach to the treatment of cancer?

In the “Integrative Oncology-Essentials Blog” (IOE Blog), I have covered a wide-range of topics pertaining to cancer treatment (i.e. from proton beam therapy to botanical medicines), managing side effects and symptoms (i.e. from exercise to acupuncture), identifying and preventing treatment-related complications (i.e. from lymphedema detection to acupuncture treatment for dry mouth), cancer prevention (i.e. from consuming an anti-cancer diet to taking baby aspirin), anti-cancer interventions and lifestyle modifications (i.e. from stress reduction to smoking cessation), and others. From time to time, we need to take a step back and simply review the overall concept of integrative oncology. What Is Integrative Oncology? [...read more...]

Mushrooms: Promising natural anti-cancer and immune modulatory effects

Posted by Brian Lawenda M.D. at 3:24 pm

Apr 182011

Mushrooms: Promising natural anti-cancer and immune modulatory effects

The medicinal use of mushrooms have been employed for over 3,000 years in the treatment of many conditions. Hundreds of peer-reviewed studies have been published indicating the wide-range of positive health effects of fungi (click on this link to see a breakdown of effects for various mushroom species), with much of the research focusing on varieties more commonly found in Asia. Human studies have found: immune stimulating/enhancing effects stimulation of cytotoxic T cells and enhanced natural killer (NK) cell activity anti-viral effects (active against: herpes, human papilloma virus, Epstein Barr virus) anti-bacterial effects anti-cancer effects (i.e. pro-apoptosis, anti-angiogenic, inhibition of [...read more...]

Learn more about prostate cancer and nutrition: the same concepts apply to most cancers and are an integral component of integrative oncology

Posted by Brian Lawenda M.D. at 4:11 pm

Mar 122011

Learn more about prostate cancer and nutrition: the same concepts apply to most cancers and are an integral component of integrative oncology

I was asked to give a short talk on this topic recently. Although it was specifically targeted to an audience interested in learning more about the role of nutrition and prostate cancer, the concepts broadly apply for most cancers. One of the most important slides is the one that highlights the fact that the “anti-cancer” diet is similar to the “heart-healthy” diet, “anti-aging” diet, “anti-diabetes” diet, “anti-Alzheimer’s” diet, “anti-inflammatory” diet, etc… (the point being: if you are following any one of these diets, you are reducing your risk of of various diseases.) Read the presentation here: Dr. Mark Moyad (University [...read more...]

New 2010 USDA Dietary Guidelines for Americans: Reduce your risk of cancer development, recurrence and progression.

Posted by Brian Lawenda M.D. at 4:18 pm

Feb 052011

*New* 2010 USDA Dietary Guidelines for Americans: Reduce your risk of cancer development, recurrence and progression.

The USDA published its’ updated dietary guidelines in late January 2011. The latest USDA dietary recommendations incorporates most of the same recommendations that are touted under different names: “Heart healthy diet” “Anti-cancer diet” “Anti-aging diet” “Anti-Alzheimer’s disease diet” “Anti-inflammatory diet” “Anti-diabetes diet” “Mediterranean diet” “Japanese diet” …and the list goes on… In summary, these are the recommendations: Consume less total fat (especially saturated fat) Maintain a healthy caloric balance (through a combined approach of calorie intake and physical activity) Increase your intake of fruits and vegetables, beans and grains Decrease your intake of processed foods, simple carbohydrates (i.e. refined sugars, [...read more...]

Integrative Oncology Basics: download the NEW 2011 free guide on integrative oncology cancer care and prevention

Posted by Brian Lawenda M.D. at 3:50 pm

Jan 102011

Integrative Oncology Basics: download the *NEW 2011* free guide on integrative oncology cancer care and prevention

Welcome to INTEGRATIVE ONCOLOGY-ESSENTIALS (IOE). My name is Dr. Brian Lawenda, and I am one of only a handful of physicians in the United States who is a radiation oncologist, integrative oncologist and medical acupuncturist. I developed the IOE WEBSITE, BLOG and the Integrative Oncology Essentials: A Patients’ Guide To Cancer Care And Prevention as a means of sharing up to date “Integrative Oncology” news, information and resources with my patients. I hope that this content is helpful to anyone living with or beyond a diagnosis of cancer.” Download the new 2011 guide here. Become a FAN to follow us [...read more...]

One “baby aspirin” per day cuts cancer death risk by up to 60%

Posted by Brian Lawenda M.D. at 8:57 am

Dec 072010

One "baby aspirin" per day cuts cancer death risk by up to 60%

A study (published in the journal, Lancet, December 2010) reports that compared with placebo, taking 75 mg of aspirin per day (one baby aspirin=81 mg) for 4 years or more reduced the risk of dying from a variety of common cancers. These results were identified through a meta-analysis of 8 placebo-controlled randomized trials (comparing placebo vs. aspirin), in 25,570 patients. These studies were designed to explore the long-term effects of aspirin. They found the following risk reduction in cancer deaths: prostate cancer (10% risk reduction) lung cancer (30% risk reduction) colon, rectal, pancreatic, and stomach cancers (40% risk reduction) esophageal [...read more...]

Green tea has no effect on breast cancer prevention: questions remain unanswered about other potential anti-cancer effects of green tea.

Posted by Brian Lawenda M.D. at 2:52 pm

Oct 282010

Green tea has no effect on breast cancer prevention: questions remain unanswered about other potential anti-cancer effects of green tea.

An excellent study (published in October 2010, in Breast Cancer Research) reported that consumption of green tea provides no benefit in reducing the risk of developing breast cancer. The authors examined the prospectively collected data on 53,793 women, in Japan, who provided information on their level of consumption of green tea over a 5-year study period. They looked at various factors to determine if there were any subcategories of women who might have experienced a reduced risk of of developing breast cancer, but they could not find any correlations (i.e. demographics, amount of green tea consumed, type of tea consumption, [...read more...]

An aspirin-a-day keeps prostate cancer away: Aspirin reduces the risk of recurrence by greater than 50%!!

Posted by Brian Lawenda M.D. at 5:31 pm

Oct 272010

An aspirin-a-day keeps prostate cancer away: Aspirin reduces the risk of recurrence by greater than 50%!!

In a fascinating study (which will be presented at the October 2010, American Society for Radiation Oncology annual meeting), investigators will be presenting the results of an analysis of 5,275 patients who had been treated for prostate cancer (with either surgery or radiation therapy.) They will be reporting that among the 1,982 men who were taking an anticoagulant medication (including aspirin) after their prostate cancer treatment, their risk of dying from prostate cancer was significantly decreased; 4% risk of death at 10 years after treatment (in patients on anticoagulant medications) vs. 10% risk of death at 10 years (in patients who were [...read more...]

Curcumin (a natural compound in curry) enhances the effects of chemotherapy

Posted by Brian Lawenda M.D. at 12:48 pm

Oct 242010

Curcumin (a natural compound in curry) enhances the effects of chemotherapy

Multiple studies have demonstrated the anti-cancer and anti-inflammatory effects of curcumin, a natural compound found in the yellow spice, turmeric (used in curry.) Research seems very promising suggesting that adding supplemental curcumin (likely as a high-dose isolated extract) may enhance the anti-cancer effects of certain chemotherapy drugs and possibly radiation therapy. To date, most of the studies have been conducted in petri dishes and in animals. A recently published manuscript (in October 2010, in Molecular Cancer Therapeutics) reported a significant cancer inhibitory effect on implanted head and neck cancer tumors (specifically, squamous cell carcinomas) in mice that were given a [...read more...]

Soy consumption may reduce the risk of breast cancer recurrence

Posted by Brian Lawenda M.D. at 9:28 pm

Oct 182010

Soy consumption may reduce the risk of breast cancer recurrence

A study (published in October 2010, in Canadian Medical Association Journal) reports that postmenopausal women with a prior history of estrogen receptor positive breast cancer had a significantly lower risk (33% less!!) of breast cancer recurrence when they consumed higher quantities of soy foods compared to those women who ate smaller quantities. Estrogen receptor positivity or sensitivity means that the breast cancer is stimulated by estrogen. The authors also reported that he risk of breast cancer recurrence was further reduced in the highest soy consumption patients who were also taking a commonly prescribed hormonal anti-cancer medication (Anastrazole.) In a study [...read more...]

Cancer patients need to select an acupuncturist with experience working with cancer.

Posted by Brian Lawenda M.D. at 3:09 pm

Sep 192010

Cancer patients need to select an acupuncturist with experience working with cancer.

Acupuncture has been shown to be an incredibly helpful therapy for patients during and after various cancer treatments (i.e. chemotherapy, surgery, radiation therapy, hormonal therapy, etc.) Studies have demonstrated efficacy in reducing stress, anxiety, depression, fatigue, hot flashes, muscle and joint pains, nausea and many other symptoms. Increasingly there are data suggesting that there may be beneficial effects on immune and inflammatory physiology. As an oncologist (and medical acupuncturist), I often recommend acupuncture to my patients. It is very important that the acupuncturist be experienced in working with cancer patients, as there are numerous important safety issues to keep in [...read more...]

Discuss ALL your medications and supplements with your cancer care team: Potentially serious interactions are common among cancer patients

Posted by Brian Lawenda M.D. at 12:54 pm

Jul 042010

Discuss ALL your medications and supplements with your cancer care team: Potentially serious interactions are common among cancer patients

Studies indicate that one-third of cancer patients take combinations of medications (both prescribed and non-prescription/over-the-counter drugs) that place them at risk of potentially dangerous interactions. (Read More Here) This number may actually be far greater after accounting for the widespread use of dietary supplements, including high-dose vitamins and various botanical/herbal therapies. To make matters even more confusing, studies have demonstrated potentially serious interactions that can occur when consuming certain foods (i.e. grapefruit) while taking medications that are metabolized by the liver. Drug-drug interactions, drug-supplement interactions and drug-food interactions can range from minor interactions that have little to no noticeable effects [...read more...]

Vitamin D decreases the risk and duration of many viral infections, including the flu and colds

Posted by Brian Lawenda M.D. at 7:10 am

Jun 182010

Vitamin D decreases the risk and duration of many viral infections, including the flu and colds

In a study published in June 2010 (in the journal PloS ONE), researchers report that in a group of patients that they followed (198 healthy adults, during the fall and winter 2009-2010) the one’s who had higher vitamin D (25-hydroxyvitamin D) levels (>/=38ng/ml) developed significantly fewer viral infections over the study period than those who had lower levels of vitamin D (17% versus 45%). Additionally, those with the higher levels of vitamin D also experienced significantly fewer days of illness (i.e. in those with influenza: 2 days of illness versus 6 days of illness, for those with the higher vitamin D [...read more...]

Drink your green tea: a green tea nutrient slows progression of a common cancer

Posted by Brian Lawenda M.D. at 5:25 pm

Jun 142010

Drink your green tea: a green tea nutrient slows progression of a common cancer

In a study presented, in June 2010, (at the American Society of Clinical Oncology annual meeting), investigators report a 69% response rate (reduction in lymphocyte count by >/=20% or a 50% reduction in lymph node size) in patients with a common leukemia type, called chronic lymphoctyic leukemia (CLL), when they received a green tea extract (EGCG). The EGCG was well tolerated with very few side effects. (Read More Here) Since this cancer often affects individuals who are diagnosed with it for many years, having a therapy that is safe and effective (and inexpensive) is an attractive option. Without more rigorous [...read more...]

Integrative Oncology Essentials: A Patients’ Guide To Cancer Care And Prevention (Free Download!!)

Posted by Brian Lawenda M.D. at 5:42 pm

May 312010

Integrative Oncology Essentials: A Patients' Guide To Cancer Care And Prevention (Free Download!!)

I have written a guide (Integrative Oncology Essentials: A Patients’ Guide To Cancer Care And Cancer Prevention) for my patients that covers many of the important topics I address in my integrative oncology lectures and consultations. I am pleased to offer this guide, as a free download (CLICK HERE: IOE Guide_V3). I really hope that the information is helpful to you, your loved ones and anyone who is interested in learning more about using integrative oncology approaches to cancer prevention and cancer care. I would be grateful to hear your comments and suggestions on how to improve future versions of this [...read more...]

Shark cartilage is NOT an effective cancer treatment- stop killing sharks for their fins!

Posted by Brian Lawenda M.D. at 9:46 am

May 282010

Shark cartilage is NOT an effective cancer treatment- stop killing sharks for their fins!

An excellent study (published in May 2010, in the Journal of the National Cancer Institute) demonstrates that shark cartilage is NOT an effective treatment for cancer. This study was conducted to evaluate the potential survival benefit of adding a pharmacologic-grade shark fin supplement to a conventional treatment regimen (chemotherapy and radiation therapy) in individuals with lung cancer. Sharks fins have been used as a cancer treatment (mainly in Asia) with the presumption that since sharks don’t develop cancer (this is actually not true- sharks do develop cancer), they must have an ‘anti-cancer’ substance within their tissues. In the current study, [...read more...]

What is Integrative Oncology? I created diagrams to illustrate the holism and complexity of this fascinating subject.

Posted by Brian Lawenda M.D. at 4:08 pm

May 072010

What is Integrative Oncology? I created diagrams to illustrate the holism and complexity of this fascinating subject.

Visit the Integrative Oncology-Essentials Website to learn more about the core principles to help prevent cancer development and cancer recurrence. I developed diagrams (CLICK HERE to see in FULL-SIZE) to help explain to my patients the core principles of integrative oncology. It shows the process of how healthy, normal cells transform into cancer cells. They demonstrate how lifestyle and behaviors can influence this process and can be used to decrease one’s risk of cancer development and progression. Importantly, the diagrams show how cancer and its’ treatment can lead to the development and exacerbation of other medical problems (Did you know that most [...read more...]

Eat your broccoli: anti-cancer phytonutrients reduce the development and growth of breast cancer cells and tumors

Posted by Brian Lawenda M.D. at 3:55 pm

May 042010

Eat your broccoli: anti-cancer phytonutrients reduce the development and growth of breast cancer cells and tumors

In a study (published in May 2010, in Clinical Cancer Research) investigators have discovered that a natural compound found in broccoli, called sulforaphane, was able to significantly decrease the number of breast cancer stem cells (the earliest cancer cells that form tumors) in cell preparation studies and in mouse studies. The authors used a highly concentrated form of this natural compound, derived from broccoli (sulforaphane), to test whether breast cancer stem cells would be able to grow and form tumors. These experiments provide further evidence that supports the anti-cancer properties of eating broccoli. (Read More Here) Sulforaphane is just one [...read more...]